Myths and mysteries about staging hepatic fibrosis by fibroscan.

The staging of hepatic fibrosis is a cornerstone of prognosis and assessment of disease progression in those with chronic liver diseases including nonalcoholic steatohepatitis (NASH). This is so because a histological assessment of fibrosis has been the only clinically applicable readout of such progression over the last century. The last ten years have, however, seen numerous changes that have challenged classical paradigms and are creating new norms for the evaluation of progression and regression of chronic liver diseases.